VERT® Focus Event 16.03.2018

Effect- and toxicity-based assessment of exhausts

Advanced and reliable hazard assessment tools for the implementation of new technology



D. Bleiner | Empa
>> Welcome

Key Adresses


A. Mayer | TTM
>> Exhaust assessment beyond the legal framework

B. Rothen-Rutishauser

>> The human lung and its susceptibility against combustion-generated and manmade nanoparticles

Assessment of Nanoparticle Properties

H. Burtscher | UASNWS
>> Relevant nanoparticle properties and how to measure them and expose them to cells

J. Czerwinski  AFHB
>> Nanoparticle emissions of combustion engines 

T. Bürki Empa
>> Nanoparticle – biobarrier interactions: Impact of particle properties on barrier penetration and functionality

Chemical Assessment of Exhausts 

N. Heeb | Empa

>> Chemistry-based assessment of combustion exhausts

M. Muñoz | Empa
>> Comparison of genotoxic potentials of diesel and gasoline vehicles

Cell-Based Assays with Specific Receptors

H.P. Nägeli University of Zurich

>> ELISA in exhaust characterization, Experiences from Arylhydrocarbon-Receptor Callux measurements

R. Schins IUF
>> Modern mutagenicity tests, Ames revisited

Alternative Cell-Based Methods to Assess Hazards of Exhausts


B. Rothen-RutishauserAMI
>> Human lung cell co-cultures – state of the art

C. Bisig | AMI
>> Lung cell responses upon diesel and GDI vehicle exposures

L. Müller UKBB
>> Impact of vehicle exhaust exposure on respiratory epithelial and natural killer cells

M. Geiser University Bern
>> Health effects of combustion and ambient aerosols on normal and diseased airway epithelia

L. Müller UKBB, P. Gehr University Bern
>> Health Impact: Solid Conclusions and Volatile Questions

Possibilities for a Toxicity-Based Legislation

C. Studer BAG

>> Options for effect- and toxicology-based legislation, the precautionary principle

N. Heeb | Empa
>> Closing remarks